Sr Supply Chain Manager

Company: Amgen
Location: Holly Springs
Posted on: March 7, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. SR MANAGER SUPPLY CHAIN (OPERATIONAL READINESS LEAD) What you will do Lets do this. Lets change the world. In this role, you will report to the Director, Supply Chain at ANC (Amgen North Carolina), and will serve as the primary Supply Chain Business Lead for the ANC2 expansion. This is a highly visible leadership role supporting design, build, and startup of our newest facility. This role is accountable for end-to-end Supply Chain operational readiness across Planning, Procurement, Materials Management, and Warehouse Operations to ensure successful facility startup and long-term operational excellence. This Sr Manager will manage Supply Chain/Warehouse startup change control records, training, documentation, risk assessments, inspection readiness and manufacturing support. The role will also represent Supply Chain in governance forums, capital project meetings, and design reviews to ensure that supply chain systems, material flows, storage strategies, and digital capabilities are embedded into the facility from design through Go-Live. As the startup is complete, this role will transition into ongoing supply chain operational leadership responsibilities within the organization. Serve as the Supply Chain point of contact for ANC2 facility design, build, and startup Develop and own the integrated Supply Chain startup schedule aligned to overall project milestones Ensure readiness of warehouse and material flow design, planning systems and ERP (SAP/WM/EWM), master data creation, procurement enablement, and inventory strategy Identify and mitigate risks impacting supply chain startup timeline Lead cross-functional readiness tracking and milestone reporting Represent Supply Chain in design reviews, steering committees, and governance meetings Provide subject matter expertise on warehouse layout, storage strategy, logistics configuration, and inventory systems Develop warehouse capacity models aligned to DS production ramp Partner with Engineering, Facilities, Technology, Quality, and Manufacturing to ensure scalable processes Partner with Supply chain procurement team to establish supply strategies for startup and PPQ readiness Support development of DS production planning and capacity assumptions Ensure compliance with cGMP, GDP, EHS, and regulatory requirements Own or support change controls, deviations, CAPAs, SOPs, and risk assessments Develop Supply Chain business continuity and risk management plans Represent Supply Chain during audits and inspections Present readiness status, risks, and mitigation plans to Site leadership Drive continuous improvement initiatives using Amgen standard tools and methods Assess impact of new requirements, changes, processes, regulations to the department Act as Supply Chain / Warehouse representative in ANC2 cross-functional projects Develop solutions to Supply Chain and cross-functional business problems through in-depth analysis, coordination, and negotiation with key decision makers. Manage issues to resolution or escalation, when required Contribute to strategic decisions affecting ANC2 Supply Chain operations Build cross-functional relationships to develop and garner support for shared programs Influence a broad spectrum of partners toward achieving business goals What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Supply Chain professional we seek is a leader with these qualifications. Basic Qualifications: High school diploma / GED and 12 years of GMP Operations and/or Supply Chain / Warehouse experience OR Associates degree and 10 years of GMP Operations and/or Supply Chain / Warehouse experience OR Bachelors degree and 8 years of GMP Operations and/or Supply Chain / Warehouse experience OR Masters degree and 6 years of GMP Operations and/or Supply Chain / Warehouse experience OR Doctorate degree and 2 years of GMP Operations and/or Supply Chain / Warehouse experience. Preferred Qualifications: 2 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing resource allocation. Experience supporting new facility startup, capital expansion, or operational readiness Expertise in regulated GMP pharmaceutical supply chain operations Strong knowledge of warehouse operations, materials planning, and procurement Supply Chain & Logistics Management, Material Management and/or engineering educational background Experience with SAP, WM/EWM, and production planning tools Demonstrated ability to build and manage integrated project plans Experience representing Supply Chain during regulatory inspections Strong business and financial acumen Lean / Six Sigma or continuous improvement experience in regulated industry Excellent organizational, communication, and interpersonal skills Experience with Change Control Management System Experience working in a global environment, ability to collaborate closely/communicate effectively at different management levels. Ability to manage complexity and manage multiple priorities, and influence without authority What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Cary , Sr Supply Chain Manager, Logistics, Transportation & Drivers , Holly Springs, North Carolina