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Scientific Associate I / II (Virus) - Infection Optimization

Company: CSL Plasma
Location: Holly Springs
Posted on: January 13, 2022

Job Description:

Job DescriptionJob PurposeThis role will provide support to Technical Development - -- -Late Stage Development on upstream projects of varying size to support cell culture and influenza candidate vaccine virus infection optimization activities.Major AccountabilitiesProcess and Product Development:Partner with diverse team members from various functions to contribute to the overarching TD team goal of influenza vaccine commercial support.Responsible for developing and maintaining mammalian cell culture (shake flasks, bioreactors, etc.) including aseptic handling of cell cultures in support of ongoing candidate vaccine virus optimization studies.-- --- --- --- --- --- --- --- -Responsible for aseptically executing experiments related to virology and mammalian cell culture including virus culture sampling, sample processing, testing and analysis with standard virology/cell culture techniques and assays.Collaboratively design small scale experiments to characterize and define optimized infection conditions for lead influenza candidate vaccine viruses.Routinely execute small scale bioreactor (ambr15 and ambr250) infection optimization of influenza candidate vaccine viruses and virus seeds.May support/participate in pilot scale studies.Troubleshooting of instrument malfunction and identifying possible route causes for study excursions/failures.-- --- -2.-- --- --- - Additional responsibilities:Responsible for summarizing and analyzing data and presenting study results.Maintain proper laboratory documentation including work instructions, lab notebooks, logbooks, appropriate electronic documentation, and lab reports.-- -Communicate (present, write-up in technical documents, etc.) results to colleagues, project teams, and management.When appropriate, follow all applicable SOPs and GMP requirements in support of lab activities.Minimum Qualifications:Bachelor's or postgraduate degree in Virology, Molecular Biology or related field.Minimum of 3 years of experience in R&D/Development setting.-- --- --- --- --- --- -Knowledge of / experience with handling and cultivation of mammalian cell cultureExperience with small scale bioreactors and automated liquid handling systems desirable.Knowledge of operation of cell culture laboratory equipment and instruments (bioreactors, bioanalyzers, cell counters, centrifuges, etc.)Knowledge of aseptic techniques.Knowledge of statistical techniques such as Design of Experiments (DOE) is desired.Knowledge of GMPs preferred.Ability to work with cross functional teams.Strong communication skills, technical writing ability, and good attention to detail.Must be a self-starter and able to work with minimal supervision.About UsOur BenefitsSeqirus is committed to attracting and retaining world-class employees who are valued for their contributions to achieving business objectives. Learn more about some of the benefits you can participate in when you join Seqirus.About SeqirusSeqirus is part of CSL Limited (ASX: CSL). As one of the largest influenza vaccine providers in the world, Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. Learn more about Seqirus.We want Seqirus to reflect the world around usAs a global organisation with employees in 35+ countries, CSL embraces diversity, equity and inclusion. Learn more about Diversity, Equity & Inclusion at Seqirus.Do work that matters at Seqirus!

Keywords: CSL Plasma, Cary , Scientific Associate I / II (Virus) - Infection Optimization, Other , Holly Springs, North Carolina

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