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Scientific Associate I / II (Virus) - Splitting Optimization

Company: CSL Plasma
Location: Holly Springs
Posted on: January 13, 2022

Job Description:

Job Description
Job Purpose:
This role will provide support to TD Late Stage Development on downstream purification projects of varying size to support influenza candidate vaccine virus splitting optimization activities under limited supervision.
Major Accountabilities
1. - - - - - - - - - - Process and Product Development:
Partner with diverse team members from various functions to contribute to the overarching TD team goal of influenza vaccine commercial support.
Responsible for small scale purification processing in support of ongoing candidate vaccine virus optimization studies.
Collaboratively design small scale experiments to characterize and define optimized viral splitting conditions for lead influenza candidate vaccine viruses.
Routinely execute small scale centrifugation and normal flow filtration experiments to optimize influenza candidate vaccine viruses and virus seeds.
May support/participate in pilot scale studies.
Troubleshooting of instrument malfunction and identifying possible root causes for study excursions/failures.
2. - - - Additional Responsibilities:
Responsible for summarizing and analyzing data, applying statistical techniques such as Design of Experiments (DOE) and presenting study results.
Maintain proper laboratory documentation including work instructions, lab notebooks, logbooks, appropriate electronic documentation, and lab reports.
Communicate (present, write-up in technical documents, etc.) results to colleagues, project teams, and management.
When appropriate, follow all applicable SOPs and GMP requirements in support of lab activities.
Minimum Qualifications:
Bachelor's or postgraduate degree in Virology, Molecular Biology or related field.
Minimum of 3 years of experience.
Knowledge of / experience in protein biochemistry and separation sciences
Knowledge of bioprocess unit operations (e.g. chromatography, centrifugation, precipitation, TFF and NFF filtration) and engineering scaling principles is desired
Knowledge of Design of Experiments (DOE) and other statistical techniques is desired
Knowledge of GMPs preferred.
Ability to work with cross functional teams.
Strong communication skills, technical writing ability, and good attention to detail.
Must be a self-starter and able to work with minimal supervision.

About Us
Our Benefits
Seqirus is committed to attracting and retaining world-class employees who are valued for their contributions to achieving business objectives. Learn more about some of the benefits you can participate in when you join Seqirus.
About Seqirus
Seqirus is part of CSL Limited (ASX: CSL). As one of the largest influenza vaccine providers in the world, Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. Learn more about Seqirus .
We want Seqirus to reflect the world around us
As a global organisation with employees in 35+ countries, CSL embraces diversity, equity and inclusion. Learn more about Diversity, Equity & Inclusion at Seqirus.
Do work that matters at Seqirus!

Keywords: CSL Plasma, Cary , Scientific Associate I / II (Virus) - Splitting Optimization, Other , Holly Springs, North Carolina

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